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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f628cca3f19ec9e598fd09cedc9644b69c03d4897d733b9127d99ddb2c7f53f3' 
  AND token = 'uCUh16xgZxs8e+HHHIBulen00LvUuas2uFspR02WTtU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}