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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8f63ee7f04650101037047ff8783a8c7d7f9d319bdba8ade43e471689735b3f9' 
  AND token = 'IloynrNEuWlKXO1YXMktNHxydAgKjLlCJIVw46wAuzI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}