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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4e946065894c4d9d77a68e00df1d55739ac605da2c430e28865a89395c26eab7' 
  AND token = 'j25X7LX+3kezpFOlrPdDEzRWd8rLY7yvMcgtS9rjZVM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}