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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '404d186661f8d9f029777fa88d48ebb3b3faef51f7ba286b2e482865a5f71909' 
  AND token = 'kqAePA/XxtviJnF0FkzL5nSNlPFmPxmgc2uY8TC4MMM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}