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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'de92a55bb9bfe53f16fbfcba4005ee9a1b7a29d0074d57f14ce9698a41334f97' 
  AND token = 'vIod3qyonOLtwPrkRnHFrRz661yv4RLwHJkxZM96LiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}