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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '722fe2b9bbeaac3c18433654f311e180b9b3ad947b053ce8d61a5fa1dc3dec1b' 
  AND token = 'EWjS34tsneKhnyILWlAa6zotg7BFpEVaH3r8Dl6cdv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}