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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '87ef0280c17418909d0e1cd15e7c79d117f9e24b229123ce69e94c135b115b35' 
  AND token = 'PeV2KGI+zGR21mFYYLrwRqpT84uWT5mzx0uLDpTda3U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}