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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c328b42df3c7b57f5031b884d87c6627de461e6efb3d78286f518abfd6a10a0b' 
  AND token = 'IGr1DKEDtcr8g6LaaKYzv++LD3SAaBPUfl5Y1KXAZK4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}