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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '6637e1ab705cc79e269fb6be2f6709b5aad67bad2737e746986c221ad42e18c6' 
  AND token = 'ZKIn7JGb29rf76Z3eUx2YHDRDRpgLYn5djFGfM7Mg0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}