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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4033ab24e91a24b8cb3da0e14e77137883a9374c0daf92432324e2024ac86e78' 
  AND token = 'CvwgsBEXSsTDHHs0R2RQRchuvDDZOXzB9HCpxjTN+fg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}