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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '309ad6a459fe06e6cf03422c8ad5aed403df77415cab69011a2678969dc1b818' 
  AND token = 'vHoFfKSW2kdApwL+HsA5M/DctjGnVw7aVVkssY7Er9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}