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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '154893cefed1104da78bfe1caeb7cce309dce09c97cdeeb16f5e24b6a1dfa707' 
  AND token = 'qqCOC6+u0ptvtB4US1lU7VNlO60g7AGsWL0V5xHxPQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}