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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e37f47f4a609ee769c92445887cdcf8dc9b3e83d3f315fc629142c845c89936f' 
  AND token = 'mexQUPM9jstL3yXlTChhM72gIlwfrA89kVSYJwXUWEQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}