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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f1cbf68dea08b144cb4067b4423794bbbf4ea94c9909ae6060f20db2541988e8' 
  AND token = 'cxrv77Do2SixeS9N8fN9mLRAEXTMQyMUS8SfGgMl8gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}