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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd5a79b1d924193bb05e42a99d3353065cc95d20fb940843b76c638963d394df4' 
  AND token = 'O39N7wH2bQxw7Nrj8bf2h7DdDXE5uehH14FXFRJ4vGg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}