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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '374b6f066cd391163faad4af2c523a4b0b67b9f55323504e0ba07c0e97cb94d6' 
  AND token = 'GRxXePwGWJjo/7lWXOGakCtyCkj9ssky6W5uZdAGYA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}