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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25336cc1090a0a15c23b74c9ee5511598dce05d3df72f9accf3ba9fa38629230' 
  AND token = 'AuFOn1jewuzU9EPFtGLSgd9oeBXPfVfV1Sid9MTKxqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}