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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '707936d385687aaec2ff71f9cd134c03f3bbf9b1f2af227d48f4a705aaea5645' 
  AND token = 'IyMdm85TvlQ7HYqpmWmXWzz+cbVYaMQx8y6flBJ7ahM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}