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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '870329a0680b07d9e681f31a416fc04a1133a70e008988972dc36bede0766c62' 
  AND token = 'faI+GIe7Tf9eRuRLzu1jS+jAAqcHWbfxtohg6ge9yj4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}