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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f5bcf99b9b0628b6abc0060b4a9a073b95bbdbe8b250c1cdfc173569eff37d96' 
  AND token = 'LUmzeCU25NczgQwkAk6n+F2hrcMQUcWXlQSE7HPOiN0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}