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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '66c36ad627834ce4c56968c7a84fdc6c2dde1a0a7365064c36ccb86f919d5254' 
  AND token = 'xJ3pBG49aXI+cM1j2g1qwDmJwe+OYY9PaktAfev0vzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}