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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '72f90d37083d3d5b2b4c78cf40b276a33b1eb33403d85d2bb1d0f946a682675b' 
  AND token = 'S+tfWThqHnM0e7NFw7CkkHhMNI4s51f+ohbCQfd1QZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}