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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '57c4a1c78780d40a9a8a086c37d83aa602e563de3365e6cbe6f008bae9f7e191' 
  AND token = 'o2MLGA8wfKHpAKlnkpOndzxTiJY+gEYd1H1x4pN/0jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}