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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e00065fd556310d1fdaed506ca2d1c395dfd1d4473df8e46835d2017b5f7185e' 
  AND token = 'KFF5uyntGvGoOMUrfDuDVRwpX7EPPPdU5Aw8xm+7RDI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}