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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '384141d0ef42685542fcaf381cf7dcac8dd9a0075020898848241eb6c1435429' 
  AND token = 'JCEBnB6jQyBM64v2BYF1v9XVjxFiCLBUEcP8C85WwOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}