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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '0a1b6528a5982c49580df4f4a484b342a46e5782896fdcacfe2a640bd2080f34' 
  AND token = 'NPZfpiEoAODNcSNEYN6JBiEOzFCYrMHaJtduqMV/fbI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}