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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2ff8708a8452f11dcd6088e9b03ee3b399445363fa1e79f209ee6a21540dd971' 
  AND token = 'obOJWEHJpxZha/6fV0s4IGdizNe69tasFpWU1D/wjaA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}