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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'd43314178d55f038a4c24fcf745828436160d57a20ff65d2c0a83a310c2a67e4' 
  AND token = 'F8tC1lDKE+56zfVwmR4SauMCQpaFObxjTRDrbgBSNF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}