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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '080357e1531b05245772dbb7b4de69a4463e06b04ca2b4c77fe40506a289021d' 
  AND token = '/KpO2gaxruWFG/GjdLaHSaCjYQfwwE5SsePBBks9cLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}