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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '490d94f8da518aabd564ed46a7ee497b080a1cf3caa3ff1df8a3d54d88e9686b' 
  AND token = 'jp2qc3t4gpaMCERBiEEn4GnIRZzjaMMd+HPKiK2rqnU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}