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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a42269481075d2e95163c7b5031dfa3763cbb5255c8d1f1224ab7906b88e11d4' 
  AND token = '63sPlfuB9/qP8ZxND7XyNLIPXBubMqB5ixe6D9kQms0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}