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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'c061b52248991270e39306708152440ee83b3148a9807b20a75ae5496c41afc0' 
  AND token = 'e8ipOSLsIKevpds6J0bdoOiVDmouOriyl/RMss3OwAs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}