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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '8a4c55cf80b11cd08db5d9e9d660f4c31afd0f87ba7f73faa6c3ca25397293c7' 
  AND token = 'hxQn1s4k5BypLhKC6qM+KBbBdmTXcNCFYMX4PTWfCYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}