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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a8cc33cb9b4a874469a04d89d321aecbcd899f0c3b5ba42de27586749820afa7' 
  AND token = 'pW1eY39KlQSbpuXteesdiVJdlwQ+9iAxZbye4Uua9AQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}