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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '60886a7f4be81f97e0d3f397a32bde7bf9e8fda745ad826217722d02a18eb451' 
  AND token = 'w7uzM+rkRWqrl8rP+mFPizIYeoen6PoodMHOh11FFa8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}