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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4ab5183d04a9cb9541c2127ae42c045bf3cc1c35967f3a21672b45d80f4c08b7' 
  AND token = '5o7HI7zmkBEwp0hN3HsIcBIcajgpoxVYQt3+OEd6gIQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}