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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'b54fc929b89e70ae6d51f41e3e661dd13a88f9ddded81e5693ab72293e46af04' 
  AND token = 'toDt5EQERLDoKa0kuWW3R9yFvbVP20aFYFSK0QaQifA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}