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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '2e7d6946fccf2a4722a4cee2dc26c4e36c41661ac74a5df33ed709f173bf435b' 
  AND token = 'gshSPWvchXjKeFrRF8Cbxhz2b2eclKg6YaZtxVldAZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}