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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f50c8f22158006110abf3723e829fa5d8a4e484fd964ce782fe5fd1be850efc4' 
  AND token = '4JLzNUHoBQr0+G3wKrN1bkEepM31meQp1jqdRrQVMCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}