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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'f1fd0eec4ce3350b93f68686503d473b1ae3ce225911c9104ce946b9fcb421d0' 
  AND token = 'nzSbLhCM3Ki+ULvoKEk0XIBx27n++NM03G+5Ym9oz7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}