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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '57f7ec52af4bee5d42498524fcbbf3d37cba2aae427668ffdd016eada0ced28c' 
  AND token = 'kCPe6lNK4/Nq3HxVKMmeZP7wzYfaDyILT8GsIUg/AM0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}