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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e0f8836d47bddc905262e74ce38a30a0d2bb3913c17128becd9be829f4688a1f' 
  AND token = 'iaTXAHFpUFMskTfVyTEMtgksxA+mk/FXLfm8JdrWKT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}