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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '9aea949e6f308d041e7b40928d3fa4efa09ac61fef8a2730dc3bfa4984ab588f' 
  AND token = '7D/W8+390TDM51/LpGhtkHQsWMEbp2U1CAKb0GzN9oE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}