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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a587b700508ed3ea2950f039eb5d7643da6ff3783ca123b855338333d719b809' 
  AND token = 'aDjbb+RhRMPHe8BCQWlPbhCo2u8ml3ilbZ1VrE/RfhE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}