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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '4a99d437d0706c64228f9ff7aec07481992a7b8ef1be62000c326171a31b2c11' 
  AND token = 'OGlGZKu3itpPl1bJ+FhMzk7G3xVzi4rMzmbkcz/1xz8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}