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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'aeeb236cbfe9343773f4972f00fde2db560bbc8aa867d61cdb753d516f2f5c58' 
  AND token = 'nsSsezsBMTQQo1IxgcqRVsBw0PELw3AWjI9sUdcMgPA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}