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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e44da9797a460403a7f72ea9376e422ebf397d502e5b147da2e65ff874b4e715' 
  AND token = '+FBdR/H4jiUmoWj/Tb7xvi3olCqvhijm4HKtp7e+szw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}