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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'e8d80d1c08ea4dbd4f83590976072b9c381db29a7d0b87a143d0941a456cbc51' 
  AND token = 'MS3NJA+RlENgjd/e5XZs11o9+R1wTA2dgtBcFx7Huwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}