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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = 'a84b0a0a9b164bb381b1fd5e3d468c77a6607e837c859f3e3a5031de09f6e49c' 
  AND token = '7Wk0PpdJCAh5RU9c+DkP1O5c1AEApcJELTtYRJMp5ok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}