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SELECT 
  1 
FROM 
  cscart_aprillock_keys 
WHERE 
  key_id = '25a771524ade1321308f08d2cb4a78a813dd3ff55f8d0e8f4745cca94d772be9' 
  AND token = 'cuAeDnFNhmKjgHnpCuCHwVF5qp9y4eenX3Q2S/9ZFOE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}